Rad51B Polyclonal Antibody

簡(jiǎn)要描述：Rad51B Polyclonal Antibody
宿主: Polyclonal, Rabbit,IgG
反應(yīng)性: Human;Mouse;Monkey
應(yīng)用: WB;IHC;IF;ELISA

產(chǎn)品型號(hào)： YP-Ab-00511

所屬分類：多克隆抗體

更新時(shí)間：2024-11-01

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詳細(xì)說明：

Rad51B Polyclonal Antibody

抗體，也叫免疫球蛋白（Ig），是一種能特異性結(jié)合抗原的糖蛋白，而抗原是在易感染動(dòng)物體內(nèi)引發(fā)抗體產(chǎn)生的物質(zhì)。在體內(nèi)，抗體是由于外源性分子的侵襲而產(chǎn)生的?？贵w以一個(gè)或者多個(gè)Y字形單體存在，每個(gè)Y字形單體由4條多肽鏈組成，包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈?zhǔn)歉鶕?jù)它們的分子量大小來(lái)命名的。Y字形結(jié)構(gòu)的頂端是可變區(qū)，為抗原結(jié)合部位。任何一個(gè)抗體的輕鏈都可以分為κ或λ型（基于小分子多肽結(jié)構(gòu)上的差異），每一個(gè)抗體的重鏈則決定了它的類或型。

產(chǎn)品詳情

Rad51B Polyclonal Antibody detects endogenous levels of Rad51B protein.

免疫原詳細(xì)信息

The antiserum was produced against synthesized peptide derived from human RAD51L1. AA range:201-250

相關(guān)試劑

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

背景

RAD51 paralog B(RAD51B) Homo sapiens The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016]

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備注：圖片僅供參考。僅供科研，不可用于臨床。

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