Rad51C Polyclonal Antibody

簡(jiǎn)要描述：Rad51C Polyclonal Antibody
宿主: Polyclonal, Rabbit,IgG
反應(yīng)性: Human;Monkey
應(yīng)用: WB;IHC;IF;ELISA

產(chǎn)品型號(hào)： YP-Ab-00512

所屬分類：多克隆抗體

更新時(shí)間：2024-11-01

詳細(xì)說(shuō)明：

Rad51C Polyclonal Antibody

抗體，也叫免疫球蛋白（Ig），是一種能特異性結(jié)合抗原的糖蛋白，而抗原是在易感染動(dòng)物體內(nèi)引發(fā)抗體產(chǎn)生的物質(zhì)。在體內(nèi)，抗體是由于外源性分子的侵襲而產(chǎn)生的。抗體以一個(gè)或者多個(gè)Y字形單體存在，每個(gè)Y字形單體由4條多肽鏈組成，包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈?zhǔn)歉鶕?jù)它們的分子量大小來(lái)命名的。Y字形結(jié)構(gòu)的頂端是可變區(qū)，為抗原結(jié)合部位。任何一個(gè)抗體的輕鏈都可以分為κ或λ型（基于小分子多肽結(jié)構(gòu)上的差異），每一個(gè)抗體的重鏈則決定了它的類或型。

產(chǎn)品詳情

Rad51C Polyclonal Antibody detects endogenous levels of Rad51C protein.

免疫原詳細(xì)信息

The antiserum was produced against synthesized peptide derived from human RAD51C. AA range:161-210

相關(guān)試劑

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

背景

RAD51 paralog C(RAD51C) Homo sapiens This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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備注：圖片僅供參考。僅供科研，不可用于臨床。

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